Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | CSGALNACT1 | Q8TDX6 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272742 | 0.91 | USP30 (0.48) | SMN1; SMN2MEN1KMT2AKDRCSGALNACT1 | |
| SCHEMBL11263470 | 0.82 | MAPK14 (0.52) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11261749 | 0.82 | RAB9A (0.46) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11299666 | 0.81 | USP30 (0.51) | SMN1; SMN2RAB9AKDRTHRBMAPT | |
| SCHEMBL11271839 | 0.79 | TRPV1 (0.46) | SMN1; SMN2MEN1KMT2ATRPV1MAPT | |
| SCHEMBL11262471 | 0.79 | TRPV1 (0.52) | TRPV1MAPT | |
| SCHEMBL11265506 | 0.79 | TRPV1 (0.44) | SMN1; SMN2MEN1KMT2ATRPV1GAA | |
| SCHEMBL11293546 | 0.78 | SMN1; SMN2 (0.61) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7599768 | 0.76 | EPHX2 (0.58) | RAB9ANPC1TRPV1GAAMAPT | |
| SCHEMBL11264322 | 0.76 | GAA (0.52) | MEN1KMT2ARAB9ANPC1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336264-A | 1-Benzoyl-3-(isoxazolyl or benzisoxazolyl)-ureas and insecticidal use thereof | ELI LILLY AND COMPANY (US) | 1982-06-22 | — | — | US | claimed |