Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22142948 | 0.87 | KDM4E (0.44) | LMNAKDM4ECYP1A2POLBHSP90AA1 | |
| SCHEMBL266824 | 0.85 | LMNA (0.70) | LMNAKDM4ECYP1A2GAAPOLB | |
| SCHEMBL11833478 | 0.78 | LMNA (0.46) | LMNAKDM4EGAAKMT2AMEN1 | |
| SCHEMBL18001725 | 0.78 | LMNA (0.54) | LMNAKDM4ECYP1A2GAAPOLB | |
| SCHEMBL1902046 | 0.77 | POLB (0.47) | LMNAKDM4EGAAPOLBAPOBEC3G | |
| SCHEMBL11347192 | 0.76 | LMNA (0.52) | LMNAKDM4ECYP1A2GAAPOLB | |
| SCHEMBL844197 | 0.74 | MEN1 (0.50) | LMNAKDM4EPOLBKMT2AMEN1 | |
| SCHEMBL5928016 | 0.73 | HSD17B10 (0.47) | LMNAKDM4ECYP1A2GAAPOLB | |
| SCHEMBL5309782 | 0.73 | HPGD (0.67) | LMNAGAAKMT2AMEN1HTT | |
| SCHEMBL3451654 | 0.72 | KDM4E (0.57) | LMNAKDM4EGAAHSP90AA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4330461-A | FIREPROOFING POLYESTERS AND POLYAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-05-18 | — | — | US | disclosed |
| US-4234729-A | FIREPROOFING POLYMERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-11-18 | — | — | US | disclosed |