Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22179679 | 0.83 | HSD17B10 (0.48) | HSD17B10L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL11272018 | 0.73 | LMNA (0.52) | L3MBTL1KDM4EMEN1KMT2AGAA | |
| SCHEMBL22179856 | 0.69 | POLB (0.54) | HSD17B10L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL11833478 | 0.68 | LMNA (0.46) | L3MBTL1KDM4EMEN1KMT2AGAA | |
| SCHEMBL1902046 | 0.67 | POLB (0.47) | KDM4EMEN1KMT2AGAALMNA | |
| SCHEMBL8751989 | 0.66 | KDM4E (0.50) | HSD17B10KDM4EMEN1KMT2ALMNA | |
| SCHEMBL6802526 | 0.66 | KDM4E (0.40) | KDM4ELMNAALDH1A1POLB | |
| SCHEMBL6803468 | 0.66 | KDM4E (0.40) | KDM4ELMNAALDH1A1POLB | |
| SCHEMBL4681763 | 0.65 | LMNA (0.61) | HSD17B10L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL17209317 | 0.65 | KMT2A (0.55) | KDM4EKMT2AGAALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060106042-A1 | Substituted heterocyclpyrmidines | BAYER CROPSCIENCE AG (DE) | 2006-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106042-A1 | Substituted heterocyclpyrmidines | DDT, ZYX, PFAS | HSD17B10 3050/4885L3MBTL1 2234/4885KDM4E 1505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.