SCHEMBL11347192

SCHEMBL11347192

CCSc1nc(C)cc(O)n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
KDM4E B2RXH2 1/20 0.45
CYP1A2 P05177 1/20 0.45
GAA P10253 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
ALDH1A1 P00352 2/20 0.42
POLB P06746 2/20 0.41
APOBEC3G Q9HC16 1/20 0.41
HSP90AA1 P07900 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ALPL P05186 1/20 0.41
ALPI P09923 1/20 0.41
ALPG P10696 1/20 0.41
PLAA Q9Y263 1/20 0.41
TSHR P16473 1/20 0.41
ATM Q13315 1/20 0.40
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21282807 0.87 HSP90AA1 (0.42) LMNAKDM4ECYP1A2HSP90AA1ATM
SCHEMBL266824 0.85 LMNA (0.70) LMNAKDM4ECYP1A2GAAL3MBTL1
SCHEMBL6495581 0.78 HSP90AA1 (0.44) L3MBTL1MEN1KMT2AALDH1A1HSP90AA1
SCHEMBL858849 0.78 LMNA (0.42) LMNAKDM4ECYP1A2ALDH1A1POLB
SCHEMBL18001725 0.78 LMNA (0.54) LMNAKDM4ECYP1A2GAAL3MBTL1
SCHEMBL1598214 0.77 KMT2A (0.49) LMNAKDM4EGAAMEN1KMT2A
SCHEMBL5309389 0.77 LMNA (0.44) LMNAKDM4EGAAL3MBTL1MEN1
SCHEMBL11830543 0.77 ALDH1A1 (0.68) CYP1A2GAAMEN1KMT2AALDH1A1
SCHEMBL11837828 0.77 ALOX15 (0.56) LMNAKDM4EGAAALDH1A1HSD17B10
SCHEMBL11272018 0.76 LMNA (0.52) LMNAKDM4ECYP1A2GAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4286045-A A SUPPORT HAVING A LAYER OF A CHALCOGENIDE OF GERMANIUM DOPED WITH SILVER OR COPPER; STABILITY; LITHOGRAPHIC PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 1981-08-25 US claimed
US-4198237-A GERMANIUM SULFIDE FUJI PHOTO FILM CO., LTD. (JP) 1980-04-15 US claimed
EP-2432776-B1 METHYL SULFANYL PYRIMIDINES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS UNIV LAVAL (CA) 2019-09-11 EP disclosed
US-4197124-A SILVER OR COPPER AND SULFUR, SELENIUM OR TELLURIUM0 FUJI PHOTO FILM CO., LTD. (JP) 1980-04-08 US disclosed
US-3951975-A INSECTICIDES, ACARICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-04-20 US disclosed