Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 14/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287046 | 0.85 | MAPK14 (0.52) | NPY5RMAPK14SMN1; SMN2MAPTMEN1 | |
| SCHEMBL11271650 | 0.83 | RXFP1 (0.46) | RXFP1NPY5RMAPK14SMN1; SMN2MAPT | |
| SCHEMBL11286892 | 0.81 | RXFP1 (0.48) | RXFP1NPY5RSMN1; SMN2MAPT | |
| SCHEMBL11283109 | 0.76 | KMT2A (0.56) | NPY5RSMN1; SMN2MAPTMEN1POLB | |
| SCHEMBL11286418 | 0.76 | RXFP1 (0.46) | RXFP1NPY5RMAPK14SMN1; SMN2MAPT | |
| SCHEMBL11273034 | 0.75 | SMN1; SMN2 (0.41) | RXFP1SMN1; SMN2MAPTPOLBGAA | |
| SCHEMBL11281897 | 0.74 | RXFP1 (0.48) | RXFP1NPY5RMAPK14SMN1; SMN2MAPT | |
| SCHEMBL11283145 | 0.73 | MAPK14 (0.47) | RXFP1NPY5RMAPK14SMN1; SMN2MAPT | |
| SCHEMBL7748808 | 0.71 | SMN1; SMN2 (0.52) | RXFP1SMN1; SMN2GAA | |
| SCHEMBL11270873 | 0.70 | MAPK14 (0.46) | NPY5RMAPK14MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | claimed |
| US-4366155-A | 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | disclosed |