Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271650 | 0.93 | RXFP1 (0.46) | SMN1; SMN2RXFP1MAPTCYP1A2CYP2C9 | |
| SCHEMBL8669219 | 0.91 | GAA (0.46) | RXFP1MAPTNPC1RAB9ANPSR1 | |
| SCHEMBL11276064 | 0.85 | HTT (0.46) | SMN1; SMN2RXFP1MAPTNPC1RAB9A | |
| SCHEMBL9135913 | 0.85 | GAA (0.45) | SMN1; SMN2RXFP1MAPTNPC1RAB9A | |
| SCHEMBL11286892 | 0.84 | RXFP1 (0.48) | SMN1; SMN2RXFP1MAPTNPBWR1MCHR1 | |
| SCHEMBL11276599 | 0.84 | TLR7 (0.43) | SMN1; SMN2MAPTNPC1RAB9ANPSR1 | |
| SCHEMBL11283145 | 0.83 | MAPK14 (0.47) | SMN1; SMN2RXFP1MAPTCYP1A2CYP2C9 | |
| SCHEMBL11274203 | 0.81 | TLR7 (0.52) | MAPTNPC1NPBWR1MCHR1KMT2A | |
| SCHEMBL11286418 | 0.79 | RXFP1 (0.46) | SMN1; SMN2RXFP1MAPTHTTNPBWR1 | |
| SCHEMBL11282702 | 0.78 | PYGL (0.48) | SMN1; SMN2RXFP1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366155-A | 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | claimed |
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | claimed |
| US-4366155-A | 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | disclosed |