Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CCR1 | P32246 | 6/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669219 | 0.93 | GAA (0.46) | RXFP1MAPTCCR1NPBWR1MCHR1 | |
| SCHEMBL11286418 | 0.92 | RXFP1 (0.46) | MAPK14RXFP1MAPTCCR1NPBWR1 | |
| SCHEMBL11271650 | 0.91 | RXFP1 (0.46) | MAPK14RXFP1MAPTCCR1NPBWR1 | |
| SCHEMBL11273156 | 0.91 | MAPK14 (0.49) | MAPK14MAPTCCR1NPBWR1MCHR1 | |
| SCHEMBL9135913 | 0.85 | GAA (0.45) | MAPK14RXFP1MAPTCCR1NPBWR1 | |
| SCHEMBL11282702 | 0.84 | PYGL (0.48) | RXFP1MAPTKMT2ASMN1; SMN2HTT | |
| SCHEMBL11281897 | 0.84 | RXFP1 (0.48) | MAPK14RXFP1MAPTCCR1NPBWR1 | |
| SCHEMBL11276599 | 0.84 | TLR7 (0.43) | MAPK14MAPTCCR1NPBWR1MCHR1 | |
| SCHEMBL11273034 | 0.83 | SMN1; SMN2 (0.41) | RXFP1MAPTCCR1NPBWR1MCHR1 | |
| SCHEMBL11267025 | 0.83 | HTT (0.48) | RXFP1MAPTKMT2ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | claimed |
| US-4366155-A | 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | disclosed |