Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260482 | 0.86 | ALDH1A1 (0.36) | MAPTALDH1A1AKR1B1CYP3A4MAPK1 | |
| SCHEMBL11270748 | 0.85 | MAPT (0.35) | MAPTALDH1A1AKR1B1MAPK1VCAM1 | |
| SCHEMBL11262598 | 0.79 | AKR1B1 (0.33) | MAPTALDH1A1AKR1B1MAPK1KDM4E | |
| SCHEMBL11269752 | 0.76 | NPC1 (0.40) | MAPTALDH1A1NPC1GAA | |
| SCHEMBL11273833 | 0.76 | ALDH1A1 (0.37) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL11272551 | 0.73 | MAPT (0.30) | MAPT | |
| SCHEMBL11266402 | 0.73 | MAPT (0.36) | MAPTALDH1A1MAPK1TSHRVCAM1 | |
| Hydrochloric Acid SCHEMBL11275024 | 0.71 | HTR2C (0.36) | MAPTALDH1A1TSHRGAA | |
| SCHEMBL11262097 | 0.71 | HTR2C (0.39) | MAPTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL19030024 | 0.68 | MAPT (0.42) | MAPTALDH1A1AKR1B1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | disclosed |