Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272587 | 0.85 | MAPT (0.35) | MAPTALDH1A1AKR1B1LMNAGAA | |
| SCHEMBL11269752 | 0.76 | NPC1 (0.40) | MAPTALDH1A1PGRGAAHIF1A | |
| SCHEMBL11262598 | 0.73 | AKR1B1 (0.33) | MAPTALDH1A1AKR1B1GAANPSR1 | |
| SCHEMBL11261985 | 0.73 | SMN1; SMN2 (0.40) | MAPTALDH1A1TDP1LMNAGAA | |
| SCHEMBL11273833 | 0.68 | ALDH1A1 (0.37) | MAPTALDH1A1LMNAGAAHTT | |
| SCHEMBL2206444 | 0.67 | ALDH1A1 (0.67) | MAPTALDH1A1PGRESPL1ATM | |
| SCHEMBL11271452 | 0.67 | CA12 (0.38) | MAPT | |
| SCHEMBL11275332 | 0.66 | MAPT (0.36) | MAPTALDH1A1TDP1GAAHTT | |
| Hydrochloric Acid SCHEMBL11275024 | 0.66 | HTR2C (0.36) | MAPTALDH1A1GAA | |
| SCHEMBL11266402 | 0.66 | MAPT (0.36) | MAPTALDH1A1TDP1HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | disclosed |