Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 3/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HSPA9 | P38646 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GAPDH | P04406 | 1/20 | 0.36 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273833 | 0.78 | ALDH1A1 (0.37) | MAPTSMN1; SMN2ALDH1A1ADRA2AADRA2B | |
| SCHEMBL6984175 | 0.77 | CHRNB4 (0.43) | NPC1MAPTRAB9ACHRNB4CHRNA3 | |
| SCHEMBL11275332 | 0.77 | MAPT (0.36) | MAPTSMN1; SMN2ALDH1A1GAAGAPDH | |
| SCHEMBL11271452 | 0.77 | CA12 (0.38) | MAPTPNMT | |
| SCHEMBL11270748 | 0.76 | MAPT (0.35) | MAPTSMN1; SMN2ALDH1A1HIF1APGR | |
| SCHEMBL11272587 | 0.76 | MAPT (0.35) | NPC1MAPTALDH1A1GAA | |
| SCHEMBL11276985 | 0.76 | CA1 (0.34) | — | |
| SCHEMBL11262097 | 0.76 | HTR2C (0.39) | MAPTALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL11260229 | 0.76 | HTR2A (0.39) | MAPTSMN1; SMN2PNMTADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL11275784 | 0.74 | CA1 (0.33) | MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | claimed |
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | disclosed |