Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 5/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11275063 | 0.91 | DGAT1 (0.39) | DGAT1SOAT1ALDH1A1LMNAMAPT | |
| SCHEMBL11278210 | 0.91 | DGAT1 (0.39) | DGAT1SOAT1ALDH1A1LMNAMAPT | |
| SCHEMBL11281207 | 0.90 | DGAT1 (0.38) | DGAT1SOAT1ALDH1A1LMNAMAPT | |
| SCHEMBL9074753 | 0.90 | ESR2 (0.40) | DGAT1SOAT1ALDH1A1LMNAMAPT | |
| SCHEMBL11284298 | 0.90 | ALDH1A1 (0.51) | DGAT1SOAT1ALDH1A1LMNAMAPT | |
| SCHEMBL9074750 | 0.90 | ESR2 (0.40) | DGAT1SOAT1ALDH1A1LMNAMAPT | |
| SCHEMBL11284940 | 0.89 | DGAT1 (0.38) | DGAT1SOAT1ALDH1A1LMNAMAPT | |
| SCHEMBL11282617 | 0.88 | HTR2C (0.51) | DGAT1SOAT1ALDH1A1LMNAMAPT | |
| SCHEMBL9073126 | 0.87 | ALDH1A1 (0.40) | DGAT1SOAT1ALDH1A1LMNAMAPT | |
| SCHEMBL11276734 | 0.87 | ALDH1A1 (0.43) | DGAT1SOAT1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4330426-A | Cyclohexylbiphenyls, their preparation and use in dielectrics and electrooptical display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-05-18 | — | — | US | disclosed |