Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11280959 | 0.90 | CYP2C9 (0.45) | FFAR1SIGMAR1HRH3PDE4APDE4B | |
| SCHEMBL11274854 | 0.88 | SIGMAR1 (0.47) | FFAR1SIGMAR1HRH3RAB9A | |
| SCHEMBL11275191 | 0.87 | RAB9A (0.39) | FFAR1SIGMAR1HRH3RAB9A | |
| SCHEMBL11284189 | 0.86 | RAB9A (0.38) | FFAR1SIGMAR1HRH3RAB9AGPR88 | |
| SCHEMBL11281220 | 0.86 | RAB9A (0.38) | SIGMAR1HRH3ACACBRAB9AGPR88 | |
| SCHEMBL11285915 | 0.85 | RAB9A (0.37) | FFAR1HRH3RAB9AGPR88 | |
| SCHEMBL11285684 | 0.85 | RAB9A (0.37) | FFAR1HRH3RAB9AGPR88 | |
| SCHEMBL11288482 | 0.85 | RAB9A (0.37) | FFAR1HRH3RAB9AGPR88 | |
| SCHEMBL11283114 | 0.85 | RAB9A (0.37) | FFAR1HRH3RAB9AGPR88 | |
| SCHEMBL11278902 | 0.85 | RAB9A (0.37) | FFAR1HRH3RAB9AGPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022183-B1 | DERIVATIVES OF CYCLOHEXYLBIPHENYL, PROCESS FOR THEIR PREPARATION, DIELECTRICS CONTAINING THEM, AND ELECTRON OPTICAL INDICATING ELEMENTS | MERCK PATENT GmbH (DE) | 1982-06-23 | — | — | EP | disclosed |
| US-4330426-A | Cyclohexylbiphenyls, their preparation and use in dielectrics and electrooptical display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-05-18 | — | — | US | disclosed |
| EP-0022183-A2 | Derivatives of cyclohexylbiphenyl, process for their preparation, dielectrics containing them, and electron optical indicating elements | MERCK PATENT GmbH (DE) | 1981-01-14 | — | — | EP | disclosed |