Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11484948 | 0.91 | LMNA (0.59) | LMNACXCR2MEN1KMT2AEPHX1 | |
| SCHEMBL11267633 | 0.84 | LMNA (0.69) | LMNACXCR2MEN1KMT2AEPHX1 | |
| SCHEMBL11490644 | 0.82 | LMNA (0.70) | LMNACXCR2MEN1KMT2AEPHX1 | |
| SCHEMBL11483687 | 0.81 | LMNA (0.92) | LMNACXCR2MEN1KMT2AEPHX1 | |
| SCHEMBL11269894 | 0.80 | LMNA (0.60) | LMNACXCR2MEN1KMT2AEPHX1 | |
| SCHEMBL11266499 | 0.80 | NPC1 (0.42) | LMNACXCR2KMT2A | |
| SCHEMBL11483511 | 0.78 | LMNA (0.69) | LMNACXCR2MEN1KMT2AEPHX1 | |
| SCHEMBL11484122 | 0.78 | LMNA (0.69) | LMNACXCR2MEN1KMT2AEPHX1 | |
| SCHEMBL3727753 | 0.78 | LMNA (0.61) | LMNACXCR2MEN1KMT2AEPHX1 | |
| SCHEMBL11261936 | 0.77 | LMNA (0.63) | LMNACXCR2MEN1KMT2AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332724-A | OXIDATION IN PRESENCE OF COBALT CATALYST | AMERICAN CYANAMID CO. (US) | 1982-06-01 | — | — | US | disclosed |