Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11401725 | 0.90 | HTT (0.64) | LMNAHTTCTSSKMT2AMEN1 | |
| SCHEMBL11484377 | 0.89 | KMT2A (0.57) | LMNAHTTCTSSKMT2AMEN1 | |
| SCHEMBL11267633 | 0.82 | LMNA (0.69) | LMNAHTTCXCR2KMT2AMEN1 | |
| SCHEMBL11747144 | 0.81 | LMNA (0.52) | LMNACXCR2KMT2AMEN1L3MBTL1 | |
| SCHEMBL11272127 | 0.81 | HTT (0.80) | LMNAHTTKMT2AMEN1DHODH | |
| SCHEMBL11260675 | 0.81 | L3MBTL1 (0.46) | LMNAHTTCTSSKMT2AMEN1 | |
| SCHEMBL11490644 | 0.80 | LMNA (0.70) | LMNAHTTCXCR2KMT2AMEN1 | |
| SCHEMBL11273026 | 0.80 | LMNA (0.62) | LMNAHTTCXCR2KMT2AMEN1 | |
| SCHEMBL11483283 | 0.79 | LMNA (0.58) | LMNAHTTCXCR2DRD4EPHX1 | |
| SCHEMBL11483687 | 0.79 | LMNA (0.92) | LMNAHTTCXCR2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332724-A | OXIDATION IN PRESENCE OF COBALT CATALYST | AMERICAN CYANAMID CO. (US) | 1982-06-01 | — | — | US | claimed |
| US-4053484-A | 1-Benzoyl-3-(4,5,6,7-tetrahydrobenzo [b]thien-4-yl)ureas and 1-benzoyl-3-(4,5,6,7-tetrahydro-7-oxobenzo [b]thien-4-yl)ureas, novel intermediates for the preparation of animal growth promoting agents | AMERICAN CYANAMID COMPANY (US) | 1977-10-11 | — | — | US | claimed |
| US-4332724-A | OXIDATION IN PRESENCE OF COBALT CATALYST | AMERICAN CYANAMID CO. (US) | 1982-06-01 | — | — | US | disclosed |
| US-4053484-A | 1-Benzoyl-3-(4,5,6,7-tetrahydrobenzo [b]thien-4-yl)ureas and 1-benzoyl-3-(4,5,6,7-tetrahydro-7-oxobenzo [b]thien-4-yl)ureas, novel intermediates for the preparation of animal growth promoting agents | AMERICAN CYANAMID COMPANY (US) | 1977-10-11 | — | — | US | disclosed |
| US-4053484-A | 1-Benzoyl-3-(4,5,6,7-tetrahydrobenzo [b]thien-4-yl)ureas and 1-benzoyl-3-(4,5,6,7-tetrahydro-7-oxobenzo [b]thien-4-yl)ureas, novel intermediates for the preparation of animal growth promoting agents | AMERICAN CYANAMID COMPANY (US) | 1977-10-11 | — | — | US | disclosed |
| US-4053484-A | 1-Benzoyl-3-(4,5,6,7-tetrahydrobenzo [b]thien-4-yl)ureas and 1-benzoyl-3-(4,5,6,7-tetrahydro-7-oxobenzo [b]thien-4-yl)ureas, novel intermediates for the preparation of animal growth promoting agents | AMERICAN CYANAMID COMPANY (US) | 1977-10-11 | — | — | US | disclosed |