Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 13/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273054 | 0.89 | TBXAS1 (0.56) | TBXAS1ALDH1A1ABL1RIN1CYP1A2 | |
| SCHEMBL11276271 | 0.82 | TBXAS1 (1.00) | TBXAS1TDP1TBXA2R | |
| SCHEMBL4123167 | 0.80 | TBXAS1 (0.48) | TBXAS1ALDH1A1ABL1RIN1CYP1A2 | |
| SCHEMBL27637869 | 0.77 | TBXAS1 (0.65) | TBXAS1CYP3A4CYP1A2TBXA2R | |
| SCHEMBL27683088 | 0.77 | TBXAS1 (0.65) | TBXAS1CYP3A4CYP1A2TBXA2R | |
| SCHEMBL5307325 | 0.77 | TBXAS1 (0.65) | TBXAS1CYP3A4CYP1A2TBXA2R | |
| SCHEMBL21191570 | 0.77 | TBXAS1 (0.65) | TBXAS1CYP3A4CYP1A2TBXA2R | |
| SCHEMBL27663546 | 0.77 | TBXAS1 (0.65) | TBXAS1CYP3A4CYP1A2TBXA2R | |
| SCHEMBL9716291 | 0.75 | TBXAS1 (0.63) | TBXAS1ALDH1A1ABL1RIN1 | |
| SCHEMBL11572618 | 0.75 | TBXAS1 (0.63) | TBXAS1ALDH1A1ABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4355170-A | ANTIINFLAMMATORY, HYPERTENSIVE, ANTIASTHMATIC AGENTS, A THROMBOXANE SYNTHETASE INHIBITORS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-10-19 | — | — | US | claimed |
| US-4355170-A | ANTIINFLAMMATORY, HYPERTENSIVE, ANTIASTHMATIC AGENTS, A THROMBOXANE SYNTHETASE INHIBITORS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-10-19 | — | — | US | disclosed |
| US-4256757-A | ANTIINFLAMMATORY AND HYPOTENSIVE AGENTS; THROMBOSIS; ASTHMA; NERVOUS SYSTEM DISORDERS | ONO PHARMACEUTICAL CO., LTD. | 1981-03-17 | — | — | US | disclosed |