Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273247 | 0.88 | CDK4 (0.39) | MAPK1ALDH1A1TSHRCDK4CCND1 | |
| SCHEMBL11263365 | 0.80 | CDK4 (0.42) | TDP1L3MBTL1ALDH1A1CDK4CCND1 | |
| SCHEMBL11255842 | 0.78 | ALDH1A1 (0.40) | MAPK1ALDH1A1CDK4CCND1SMN1; SMN2 | |
| SCHEMBL19577299 | 0.77 | MAPT (0.39) | L3MBTL1ALDH1A1TSHRCDK4CCND1 | |
| SCHEMBL11259485 | 0.77 | LTB4R (0.44) | ALDH1A1CDK4CCND1SMN1; SMN2 | |
| SCHEMBL11503539 | 0.76 | CDK4 (0.43) | TDP1L3MBTL1ALDH1A1CDK4CCND1 | |
| SCHEMBL11203242 | 0.76 | TDP1 (0.55) | TDP1MEN1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL11264455 | 0.75 | ALDH1A1 (0.42) | TDP1L3MBTL1ALDH1A1TSHRCDK4 | |
| SCHEMBL11262458 | 0.73 | MAPT (0.42) | TDP1KMT2AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL11038591 | 0.73 | PPARA (0.51) | TDP1MEN1KMT2AL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003532-B1 | OMEGA-(2-(N-LOWER ALKYL-BENZAMIDO)-PHENYL)-ALKANOIC ACIDS, THEIR USE AND PREPARATION, AND MEDICAMENTS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-04-28 | — | — | EP | disclosed |
| EP-0003532-A1 | Omega-(2-(N-lower alkyl-benzamido)-phenyl)-alkanoic acids, their use and preparation, and medicaments containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1979-08-22 | — | — | EP | disclosed |