Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 5/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273128 | 0.88 | TDP1 (0.43) | CDK4CCND1ALDH1A1SMN1; SMN2UTS2R | |
| SCHEMBL11255842 | 0.85 | ALDH1A1 (0.40) | CDK4CCND1ALDH1A1SMN1; SMN2TMEM97 | |
| SCHEMBL11263365 | 0.85 | CDK4 (0.42) | CDK4CCND1ALDH1A1SMN1; SMN2TMEM97 | |
| SCHEMBL11259485 | 0.84 | LTB4R (0.44) | CDK4CCND1ALDH1A1SMN1; SMN2TMEM97 | |
| SCHEMBL11264455 | 0.82 | ALDH1A1 (0.42) | CDK4CCND1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11503539 | 0.81 | CDK4 (0.43) | CDK4CCND1ALDH1A1SMN1; SMN2TMEM97 | |
| SCHEMBL19577299 | 0.80 | MAPT (0.39) | CDK4CCND1ALDH1A1SMN1; SMN2TMEM97 | |
| SCHEMBL11257623 | 0.75 | HDAC3 (0.45) | ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL11262457 | 0.74 | MAPT (0.36) | CDK4CCND1ALDH1A1LMNATSHR | |
| SCHEMBL11262458 | 0.73 | MAPT (0.42) | ALDH1A1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003532-B1 | OMEGA-(2-(N-LOWER ALKYL-BENZAMIDO)-PHENYL)-ALKANOIC ACIDS, THEIR USE AND PREPARATION, AND MEDICAMENTS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-04-28 | — | — | EP | disclosed |
| US-4322439-A | ω-[2-(N-Lower alkyl-benzamido)-phenyl]-alkanoic acids, their use, and medicaments containing them | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-03-30 | — | — | US | disclosed |
| WO-1979000586-A1 | W-(2-N-LOWER ALKYL-BENZAMIDO)-PHENYL)-ALKANOIC ACIDS,THEIR USE AND PREPARATION,AND MEDICAMENTS CONTAINING THEM | BYK GULDEN LOMBERG CHEM FAB (DE) | 1979-08-23 | — | — | WO | disclosed |