Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17A | Q9UEE5 | 5/20 | 0.33 |
| ▸ | STK17B | O94768 | 3/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | GCKR | Q14397 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | RHOC | P08134 | 1/20 | 0.32 |
| ▸ | RHOA | P61586 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273159 | 0.85 | STK17A (0.32) | STK17ASTK17BBCHEACHEPOLB | |
| SCHEMBL11272364 | 0.83 | NR1H2 (0.35) | STK17ANR1H2NR1H3POLB | |
| SCHEMBL11279678 | 0.78 | AR (0.41) | ARNR1H2NR1H3 | |
| SCHEMBL11262896 | 0.76 | RORC (0.36) | ARNR1H2NR1H3GCKGCKR | |
| SCHEMBL16702836 | 0.75 | AR (0.39) | ARNR1H2NR1H3GCKGCKR | |
| SCHEMBL11275694 | 0.75 | STK17A (0.33) | STK17ASTK17BBCHEACHEPOLB | |
| SCHEMBL11268219 | 0.74 | NR1H3 (0.38) | ARNR1H2NR1H3POLB | |
| SCHEMBL11264839 | 0.73 | NR1H2 (0.35) | ARNR1H2NR1H3 | |
| Hydrochloric Acid SCHEMBL28300035 | 0.72 | MRGPRX4 (0.35) | RHOCRHOAPOLB | |
| SCHEMBL11356015 | 0.70 | SMN1; SMN2 (0.35) | STK17AARPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322434-A | N-Substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto | SCHERING CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| US-4267193-A | N-substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto | SCHERING CORPORATION (US) | 1981-05-12 | — | — | US | disclosed |