Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17A | Q9UEE5 | 5/20 | 0.32 |
| ▸ | STK17B | O94768 | 3/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273155 | 0.85 | STK17A (0.33) | STK17ASTK17BBCHEACHEPOLB | |
| SCHEMBL11272367 | 0.84 | MEN1 (0.33) | STK17APOLBIDO1 | |
| SCHEMBL11279682 | 0.79 | THRB (0.36) | — | |
| SCHEMBL11262905 | 0.77 | MEN1 (0.33) | — | |
| SCHEMBL11268221 | 0.75 | CDC25A (0.33) | — | |
| SCHEMBL11264841 | 0.75 | KDM4E (0.31) | — | |
| SCHEMBL11356017 | 0.71 | STK17A (0.33) | STK17APOLB | |
| Hydrochloric Acid SCHEMBL28300035 | 0.70 | MRGPRX4 (0.35) | POLBIDO1 | |
| SCHEMBL11272364 | 0.69 | NR1H2 (0.35) | STK17APOLB | |
| Hydrochloric Acid SCHEMBL11266399 | 0.68 | ACHE (0.30) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322434-A | N-Substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto | SCHERING CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| US-4267193-A | N-substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto | SCHERING CORPORATION (US) | 1981-05-12 | — | — | US | disclosed |