Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 2/20 | 0.34 |
| ▸ | GCKR | Q14397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11268219 | 0.86 | NR1H3 (0.38) | RORCNR1H3NR1H2MEN1LMNA | |
| SCHEMBL11262905 | 0.85 | MEN1 (0.33) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL11261894 | 0.83 | PGR (0.38) | RORCNR1H3NR1H2MEN1LMNA | |
| SCHEMBL11264342 | 0.78 | MLYCD (0.35) | RORCNR1H3NR1H2LMNASMN1; SMN2 | |
| SCHEMBL11273155 | 0.76 | STK17A (0.33) | NR1H3NR1H2GCKGCKRPOLB | |
| SCHEMBL16702836 | 0.75 | AR (0.39) | RORCNR1H3NR1H2MEN1LMNA | |
| SCHEMBL11279678 | 0.72 | AR (0.41) | NR1H3NR1H2MEN1KMT2AHTT | |
| SCHEMBL11268221 | 0.72 | CDC25A (0.33) | NR1H3NR1H2MEN1LMNAMAPT | |
| SCHEMBL10821306 | 0.70 | MGLL (0.42) | MEN1LMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL16709914 | 0.69 | ALDH1A1 (0.42) | RORCNR1H3NR1H2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322434-A | N-Substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto | SCHERING CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| US-4267193-A | N-substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto | SCHERING CORPORATION (US) | 1981-05-12 | — | — | US | disclosed |