Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK6 | P43250 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CDC25B | P30305 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12490981 | 0.77 | NOD2 (0.55) | GRK6SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL11338215 | 0.72 | TSHR (0.63) | MAPTRAB9ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL30995157 | 0.72 | NOD2 (0.53) | GRK6SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL8927648 | 0.70 | TSHR (0.70) | MAPTRAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL29389855 | 0.70 | TSHR (0.70) | MAPTRAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL11273243 | 0.69 | KMT2A (0.42) | MAPTRAB9AMAPK1ALDH1A1KMT2A | |
| SCHEMBL31505722 | 0.69 | NOD2 (0.50) | GRK6SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL15642774 | 0.69 | NOD2 (0.50) | GRK6SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL571295 | 0.69 | CA12 (0.59) | MAPTRAB9ASMN1; SMN2HCRTR1ALDH1A1 | |
| SCHEMBL30684671 | 0.69 | CA12 (0.59) | MAPTRAB9ASMN1; SMN2HCRTR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4351842-A | N-Cyclopropylisoindolines | GLAXO LABORATORIES LIMITED (GB) | 1982-09-28 | — | — | US | disclosed |