Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11275259 | 0.71 | KDM4E (0.42) | KMT2AKDM4EPKMALDH1A1MEN1 | |
| SCHEMBL11273241 | 0.69 | GRK6 (0.49) | KMT2AKDM4ERAB9AALDH1A1MEN1 | |
| SCHEMBL8106785 | 0.69 | CHRM1 (0.47) | — | |
| SCHEMBL22194510 | 0.69 | KDM4E (0.45) | KMT2AKDM4EAPOBEC3AAPOBEC3GPKM | |
| Hydrochloric Acid SCHEMBL30028644 | 0.67 | CYP3A4 (0.39) | KMT2AKDM4EALDH1A1MEN1MAPT | |
| SCHEMBL10746773 | 0.67 | ALDH1A1 (0.40) | KMT2AKDM4EAPOBEC3AAPOBEC3GPKM | |
| SCHEMBL4139032 | 0.67 | SLC6A4 (0.48) | — | |
| SCHEMBL4139034 | 0.67 | SLC6A4 (0.48) | — | |
| SCHEMBL12490981 | 0.66 | NOD2 (0.55) | KMT2AKDM4EALDH1A1MEN1OPRM1 | |
| SCHEMBL5422670 | 0.65 | KMT2A (0.64) | KMT2AKDM4EPKMALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4351842-A | N-Cyclopropylisoindolines | GLAXO LABORATORIES LIMITED (GB) | 1982-09-28 | — | — | US | disclosed |