Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11717764 | 0.80 | RAB9A (0.47) | GAATP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11712622 | 0.80 | MAPT (0.43) | GAAALDH1A1TP53KMT2AMEN1 | |
| SCHEMBL11279397 | 0.78 | ALDH1A1 (0.43) | GAAALDH1A1ALOX15CES2CES1 | |
| SCHEMBL28014540 | 0.77 | ALDH1A1 (0.42) | GAAALDH1A1ALOX15CES2CES1 | |
| SCHEMBL11716804 | 0.74 | MAPT (0.50) | GAAALDH1A1ALOX15TP53KMT2A | |
| SCHEMBL10828905 | 0.74 | GAA (0.56) | GAAALDH1A1ALOX15CES2CES1 | |
| SCHEMBL3577408 | 0.74 | ALDH1A1 (0.40) | GAAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL30473132 | 0.74 | ALDH1A1 (0.40) | GAAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11715314 | 0.73 | ALDH1A1 (0.45) | GAAALDH1A1CES2CES1TP53 | |
| SCHEMBL21666258 | 0.72 | MAP2K3 (0.56) | GAAALDH1A1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31071-E | 6-Aza-3H-1,4-benzodiazepines | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1982-11-02 | — | — | US | disclosed |
| US-4008223-A | SPASMOLYTIC, ANTIPHLOGISTIC, TRANQUILIZER | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1977-02-15 | — | — | US | disclosed |