SCHEMBL11273571

SCHEMBL11273571

OC(Cc1ccccc1)(Cn1ccnc1)c1ccc(Cl)cc1Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OGG1 O15527 1/20 0.55
PTGS2 P35354 1/20 0.53
CYP27B1 O15528 1/20 0.50
PDCD1 Q15116 1/20 0.49
CD274 Q9NZQ7 1/20 0.49
IDO1 P14902 3/20 0.47
CYP11B1 P15538 4/20 0.46
CYP11B2 P19099 4/20 0.46
CYP3A4 P08684 5/20 0.46
CYP1A2 P05177 3/20 0.46
CYP2D6 P10635 3/20 0.46
CYP19A1 P11511 2/20 0.46
TBXAS1 P24557 2/20 0.46
MAPT P10636 2/20 0.46
POLB P06746 1/20 0.46
QPCT Q16769 1/20 0.46
CYP4Z1 Q86W10 1/20 0.46
QPCTL Q9NXS2 1/20 0.46
ADRA2C P18825 2/20 0.44
CYP2C9 P11712 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11275277 0.93 OGG1 (0.57) OGG1PTGS2CYP27B1PDCD1CD274
Nitric Acid SCHEMBL11271858 0.93 PTGS2 (0.50) OGG1PTGS2CYP27B1PDCD1CD274
Hydrochloric Acid SCHEMBL11274202 0.92 OGG1 (0.56) OGG1PTGS2CYP27B1PDCD1CD274
SCHEMBL11264925 0.91 OGG1 (0.46) OGG1PTGS2CYP27B1PDCD1CD274
SCHEMBL11272817 0.89 OGG1 (0.53) OGG1PTGS2CYP27B1PDCD1CD274
SCHEMBL11268747 0.87 OGG1 (0.54) OGG1PTGS2CYP27B1PDCD1CD274
SCHEMBL11266968 0.86 OGG1 (0.57) OGG1PTGS2CYP27B1PDCD1CD274
Nitric Acid SCHEMBL11270419 0.85 CYP3A4 (0.44) OGG1PTGS2CYP27B1PDCD1CD274
SCHEMBL10916395 0.84 OGG1 (0.61) OGG1PTGS2CYP27B1PDCD1CD274
SCHEMBL9665470 0.84 OGG1 (0.61) OGG1PTGS2CYP27B1PDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4358458-A BACTERICIDE, FUNGICIDES NORDMARK-WERKE GMBH (DE) 1982-11-09 US claimed