Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 7/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.36 |
| ▸ | CHRNG | P07510 | 2/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | CHRND | Q07001 | 2/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121021 | 0.82 | SLC6A4 (0.37) | SLC6A4SLC6A3SLC6A2CHRNA1CHRNG | |
| SCHEMBL11140706 | 0.81 | OPRM1 (0.46) | SMN1; SMN2KDM4E | |
| SCHEMBL10876682 | 0.81 | SLC6A4 (0.40) | UTS2RSLC6A4SLC6A3SLC6A2CHRNA1 | |
| SCHEMBL9667383 | 0.79 | SLC6A4 (0.38) | UTS2RSLC6A4SLC6A3SLC6A2CHRNA1 | |
| SCHEMBL867470 | 0.77 | UTS2R (0.36) | UTS2RSLC6A4SLC6A3SLC6A2CHRNA1 | |
| SCHEMBL28318484 | 0.77 | CYP3A4 (0.39) | SLC6A4SLC6A3SLC6A2LMNASMN1; SMN2 | |
| SCHEMBL27997493 | 0.75 | MMP2 (0.47) | — | |
| SCHEMBL2307573 | 0.75 | MMP2 (0.47) | — | |
| SCHEMBL10638461 | 0.75 | UTS2R (0.38) | UTS2RSLC6A4SLC6A3SLC6A2CHRNA1 | |
| SCHEMBL8807095 | 0.74 | UTS2R (0.38) | UTS2RSLC6A4SLC6A3SLC6A2CHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049913-A2 | New ethenylimidazole derivatives, processes for their preparation and pharmaceutical compositions containing them; intermediates, useful in their preparation and a process for the preparation thereof | GIST-BROCADES N.V. (NL) | 1982-04-21 | — | — | EP | disclosed |