Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1988718 | 0.87 | CHRNA7 (0.41) | MAPTALDH1A1HTTLMNAPOLB | |
| SCHEMBL1994121 | 0.85 | ALDH1A1 (0.43) | MAPTALDH1A1HTTLMNAPOLB | |
| SCHEMBL1126898 | 0.83 | TRPV1 (0.41) | MAPTALDH1A1HTTLMNAPOLB | |
| SCHEMBL1990351 | 0.83 | DGAT1 (0.42) | MAPTALDH1A1HTTLMNAPOLB | |
| SCHEMBL2007078 | 0.83 | REV1 (0.40) | MAPTALDH1A1HTTLMNAPOLB | |
| SCHEMBL1993691 | 0.83 | MAPT (0.42) | MAPTALDH1A1HTTLMNAPOLB | |
| SCHEMBL1993154 | 0.82 | MAPT (0.43) | MAPTALDH1A1HTTLMNAPOLB | |
| SCHEMBL1127445 | 0.81 | TRPV1 (0.39) | MAPTALDH1A1HTTLMNAPOLB | |
| SCHEMBL1988085 | 0.80 | MAPT (0.42) | MAPTALDH1A1HTTLMNAPOLB | |
| SCHEMBL1126932 | 0.79 | MAPT (0.38) | MAPTALDH1A1HTTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | claimed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | claimed |