Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1270807 | 0.88 | LMNA (0.51) | TDP1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL10915717 | 0.82 | LMNA (0.47) | TDP1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL84134 | 0.81 | ALDH1A1 (0.49) | TDP1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL11790891 | 0.79 | ALDH1A1 (0.48) | TDP1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL5967396 | 0.77 | KEAP1 (0.47) | TDP1ALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL8905179 | 0.77 | ALDH1A1 (0.47) | TDP1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL7624972 | 0.77 | LMNA (0.49) | TDP1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL11274023 | 0.77 | TDP1 (0.49) | TDP1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL11732537 | 0.77 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTHPGDENPP2 | |
| SCHEMBL6558020 | 0.76 | ALDH1A1 (0.59) | TDP1ALDH1A1LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310460-A | Process for the production of 6-D-α-amino-p-hydroxyphenylacetamido penicillanic acid | DOBFAR S.P.A. (IT) | 1982-01-12 | — | — | US | disclosed |