Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11275045 | 0.89 | ALDH1A1 (0.59) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL6601536 | 0.83 | KDM4E (0.64) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL6215102 | 0.82 | KDM4E (0.68) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL2395969 | 0.81 | ALDH1A1 (0.66) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL11407980 | 0.80 | MEN1 (0.65) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL11282487 | 0.80 | KDM4E (0.57) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL7107150 | 0.79 | KDM4E (0.69) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL11430874 | 0.79 | ALDH1A1 (0.64) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL4604800 | 0.79 | ALDH1A1 (0.64) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL18569422 | 0.79 | KDM4E (0.72) | KDM4EALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349526-A | TRI-SUBSTITUTED PHENYLUREAS AS SOLVENT IN ANTHRAQUINONE PROCESS | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1982-09-14 | — | — | US | disclosed |