Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | MITF | O75030 | 1/20 | 0.59 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11274060 | 0.89 | KDM4E (0.60) | ALDH1A1NPC1KMT2ARAB9AKDM4E | |
| SCHEMBL11282486 | 0.85 | ATM (0.56) | ALDH1A1NPC1KMT2ARAB9AKDM4E | |
| SCHEMBL5332530 | 0.85 | ATM (0.56) | ALDH1A1NPC1KMT2ARAB9AKDM4E | |
| SCHEMBL6601536 | 0.81 | KDM4E (0.64) | ALDH1A1NPC1KMT2ARAB9AKDM4E | |
| SCHEMBL6215102 | 0.81 | KDM4E (0.68) | ALDH1A1NPC1KMT2ARAB9AKDM4E | |
| SCHEMBL2395969 | 0.80 | ALDH1A1 (0.66) | ALDH1A1NPC1KMT2ARAB9AKDM4E | |
| SCHEMBL11407980 | 0.79 | MEN1 (0.65) | ALDH1A1NPC1KMT2ARAB9AKDM4E | |
| SCHEMBL11282487 | 0.79 | KDM4E (0.57) | ALDH1A1NPC1KMT2ARAB9AKDM4E | |
| SCHEMBL11430874 | 0.78 | ALDH1A1 (0.64) | ALDH1A1NPC1KMT2ARAB9AKDM4E | |
| SCHEMBL7107150 | 0.78 | KDM4E (0.69) | ALDH1A1NPC1KMT2ARAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349526-A | TRI-SUBSTITUTED PHENYLUREAS AS SOLVENT IN ANTHRAQUINONE PROCESS | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1982-09-14 | — | — | US | disclosed |