Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | DRD4 | P21917 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177908 | 0.81 | CYP1A2 (0.63) | DRD2DRD4DRD3CYP1A2CYP2D6 | |
| SCHEMBL10919844 | 0.79 | KMT2A (0.55) | DRD2DRD4DRD3CYP1A2CYP2D6 | |
| SCHEMBL13918745 | 0.79 | ALDH1A1 (0.55) | MAPK1TSHRAHRALDH1A1KMT2A | |
| SCHEMBL12963416 | 0.79 | ALDH1A1 (0.55) | MAPK1TSHRAHRALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL10924876 | 0.78 | KMT2A (0.54) | DRD2DRD4DRD3CYP1A2CYP2D6 | |
| Formic Acid SCHEMBL6325584 | 0.78 | DRD2 (0.59) | DRD2DRD4DRD3ALDH1A1RECQL | |
| SCHEMBL23457915 | 0.77 | AHR (0.65) | CYP2D6TSHRAHRALDH1A1CNR1 | |
| SCHEMBL26976511 | 0.77 | AHR (0.65) | CYP2D6TSHRAHRALDH1A1CNR1 | |
| SCHEMBL14848719 | 0.75 | AHR (0.58) | TSHRAHRALDH1A1CNR1CNR2 | |
| SCHEMBL13330470 | 0.74 | MEN1 (0.49) | TSHRHTR1BALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0066987-A2 | N-(aryloxyalkyl)-N'-(amino-alkyl) ureas | A.H. ROBINS COMPANY, INCORPORATED (US) | 1982-12-15 | — | — | EP | disclosed |