Formic Acid

Formic Acid

SCHEMBL6325584

CCCNCCOc1ccc(OC)cc1.O=CO

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.59
DRD4 P21917 2/20 0.59
DRD3 P35462 2/20 0.59
MTNR1A P48039 1/20 0.55
MTNR1B P49286 1/20 0.55
KMT2A Q03164 2/20 0.51
MEN1 O00255 1/20 0.51
RYR2 Q92736 1/20 0.50
NPC1 O15118 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
HEXA P06865 1/20 0.46
HEXB P07686 1/20 0.46
ALDH1A1 P00352 4/20 0.46
NPSR1 Q6W5P4 1/20 0.46
KDM4E B2RXH2 3/20 0.45
RECQL P46063 1/20 0.45
MAPT P10636 1/20 0.45
LTA4H P09960 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL5075586 0.83 MTNR1A (0.58) DRD2DRD4DRD3MTNR1AMTNR1B
Formic Acid SCHEMBL5075583 0.82 MTNR1A (0.57) DRD2DRD4DRD3MTNR1AMTNR1B
Formic Acid SCHEMBL6327968 0.80 DRD2 (0.61) DRD2DRD4DRD3KMT2AMEN1
SCHEMBL7451259 0.80 LMNA (0.58) DRD2DRD4DRD3SMN1; SMN2ALDH1A1
SCHEMBL30969268 0.79 MAPT (0.70) KMT2AMEN1NPC1SMN1; SMN2HEXA
SCHEMBL14294277 0.78 DRD2 (0.79) DRD2DRD4DRD3NPC1KDM4E
SCHEMBL11274141 0.78 DRD2 (0.50) DRD2DRD4DRD3MTNR1AMTNR1B
SCHEMBL30969225 0.77 TSHR (0.65)
Formic Acid SCHEMBL6325576 0.77 CYP1A2 (0.64) SMN1; SMN2ALDH1A1KDM4ERECQLMAPT
Hydrochloric Acid SCHEMBL8057930 0.77 DRD4 (0.79) DRD2DRD4DRD3MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1501830-A1 7-ARYL-3,9-DIAZABICYCLO[3.3.1]NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES Actelion Pharmaceuticals Ltd. (CH) 2005-02-02 EP disclosed
WO-2003093267-A1 7-ARYL-3,9-DIAZABICYCLO(3.3.1)NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES ACTELION PHARMACEUTICALS LTD (CH) 2003-11-13 WO disclosed