Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.58 |
| ▸ | SRC | P12931 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 4/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SCN1A | P35498 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10812265 | 0.87 | LTA4H (0.56) | NPC1RAB9ALTA4HHRH3TSHR | |
| Hydrochloric Acid SCHEMBL10814604 | 0.85 | LTA4H (0.55) | NPC1RAB9AKMT2ALTA4HHRH3 | |
| SCHEMBL9827046 | 0.85 | MAOB (0.58) | NPC1RAB9ALTA4HHRH3TSHR | |
| SCHEMBL11262246 | 0.84 | HRH3 (0.59) | ALDH1A1KDM4EMEN1KMT2ALTA4H | |
| Hydrochloric Acid SCHEMBL4576347 | 0.84 | MAOB (0.56) | NPC1RAB9AKMT2ALTA4HHRH3 | |
| SCHEMBL30103286 | 0.83 | ALDH1A1 (0.55) | ALDH1A1KDM4EFGFR1SRCNPC1 | |
| SCHEMBL22529784 | 0.83 | KDM4E (0.55) | ALDH1A1KDM4EFGFR1SRCNPC1 | |
| SCHEMBL6386440 | 0.83 | KDM4E (0.55) | ALDH1A1KDM4EFGFR1SRCNPC1 | |
| SCHEMBL4420934 | 0.82 | NPC1 (0.65) | ALDH1A1KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL21642566 | 0.82 | KDM4E (0.65) | ALDH1A1KDM4EFGFR1SRCNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314061-A | Certain 3,6-bis-(heteroaminoalkoxy) acridines | AMERICAN CYANAMID COMPANY | 1982-02-02 | — | — | US | claimed |
| EP-0031407-A1 | Substituted 3,6 bis-(aminoalkoxy)acridines, and a process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1981-07-08 | — | — | EP | claimed |
| US-4314061-A | Certain 3,6-bis-(heteroaminoalkoxy) acridines | AMERICAN CYANAMID COMPANY | 1982-02-02 | — | — | US | disclosed |
| EP-0031407-A1 | Substituted 3,6 bis-(aminoalkoxy)acridines, and a process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1981-07-08 | — | — | EP | disclosed |