Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11866574 | 0.71 | MAPK14 (0.38) | FGFR1HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL11866098 | 0.70 | CYP1A2 (0.37) | FGFR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11864936 | 0.70 | GCK (0.41) | HPGDMEN1KMT2AALDH1A1THRB | |
| SCHEMBL9279585 | 0.69 | KDM4E (0.44) | HPGDMEN1KMT2AALDH1A1THRB | |
| SCHEMBL11866856 | 0.68 | FBP1 (0.36) | FGFR1ALDH1A1KDM4EHSD17B10POLB | |
| SCHEMBL11868560 | 0.68 | GCK (0.40) | FGFR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11870218 | 0.67 | ALDH1A1 (0.34) | FGFR1MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL11396941 | 0.65 | THRB (0.48) | ALDH1A1THRBKDM4EHSD17B10POLB | |
| SCHEMBL11529719 | 0.65 | POLB (0.78) | KMT2AMAPK1KDM4EPOLBRAB9A | |
| SCHEMBL11478965 | 0.65 | POLB (0.56) | MEN1KMT2AALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353913-A | ANTHELMINTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1982-10-12 | — | — | US | disclosed |
| US-4287199-A | USEFUL AS ANTHELMINITICS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-01 | — | — | US | disclosed |