Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 9/20 | 0.81 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.81 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | TLR4 | O00206 | 1/20 | 0.59 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.59 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.59 |
| ▸ | MLNR | O43193 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22279186 | 1.00 | ADRB2 (0.81) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL11364046 | 0.95 | ADRB2 (0.73) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL16550063 | 0.88 | ADRB2 (0.73) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL11279285 | 0.88 | ADRB1 (0.66) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL27773039 | 0.86 | ADRB2 (0.68) | ADRB2ADRB1ADRB3ADRA1A | |
| SCHEMBL17950815 | 0.86 | ADRB2 (0.70) | ADRB2ADRB1ADRB3KMT2ADRD2 | |
| SCHEMBL11279000 | 0.85 | ADRB1 (0.60) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL9320639 | 0.84 | ADRB2 (0.74) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL11275123 | 0.84 | ADRB2 (0.74) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL10346478 | 0.83 | ADRB2 (0.72) | ADRB2ADRB1ADRB3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064487-A1 | New substituted 3-(parasubstituted)phenoxy-1-alkylamino-propanol-2-s, as well as process for their preparation, pharmaceutical preparations containing same, and method for treating cardiac failure | Aktiebolaget Hässle (SE) | 1982-11-10 | — | — | EP | disclosed |