Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 11/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 10/20 | 0.66 |
| ▸ | ADRB3 | P13945 | 11/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22279186 | 0.88 | ADRB2 (0.81) | ADRB1ADRB2ADRB3DRD2DRD4 | |
| SCHEMBL11274264 | 0.88 | ADRB2 (0.81) | ADRB1ADRB2ADRB3DRD2DRD4 | |
| SCHEMBL11279000 | 0.88 | ADRB1 (0.60) | ADRB1ADRB2ADRB3CYP1A2ATM | |
| SCHEMBL9320639 | 0.87 | ADRB2 (0.74) | ADRB1ADRB2ADRB3CYP1A2ATM | |
| SCHEMBL11275123 | 0.87 | ADRB2 (0.74) | ADRB1ADRB2ADRB3CYP1A2ATM | |
| Hydrochloric Acid SCHEMBL10346478 | 0.85 | ADRB2 (0.72) | ADRB1ADRB2ADRB3CYP1A2ATM | |
| SCHEMBL11364046 | 0.82 | ADRB2 (0.73) | ADRB1ADRB2ADRB3ATMDRD2 | |
| SCHEMBL11355780 | 0.82 | ATM (0.59) | ADRB1ADRB2ADRB3CYP1A2ATM | |
| SCHEMBL11360960 | 0.82 | KDM4E (0.58) | ADRB1ADRB2ADRB3CYP1A2MEN1 | |
| SCHEMBL11356662 | 0.81 | ADRB2 (0.54) | ADRB1ADRB2ADRB3CYP1A2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064487-A1 | New substituted 3-(parasubstituted)phenoxy-1-alkylamino-propanol-2-s, as well as process for their preparation, pharmaceutical preparations containing same, and method for treating cardiac failure | Aktiebolaget Hässle (SE) | 1982-11-10 | — | — | EP | disclosed |