SCHEMBL1127441

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1127486	0.83	ALDH1A1 (0.42)	ALDH1A1TSHRHPGDGLA
	SCHEMBL1127130	0.81	ALDH1A1 (0.41)	ALDH1A1CYP1A2CYP3A4CYP2C9HSD17B10
	SCHEMBL27756589	0.78	TLR8 (0.42)	ALDH1A1APOBEC3GHPGDKDM4E
	SCHEMBL1126659	0.76	GLA (0.40)	ALDH1A1CYP1A2CYP3A4HSD17B10ALOX15
	SCHEMBL1126698	0.74	POLB (0.38)	ALDH1A1HSD17B10HPGDKDM4E
	SCHEMBL28131241	0.72	ALDH1A1 (0.41)	ALDH1A1L3MBTL1CYP1A2CYP3A4HSD17B10
	SCHEMBL1126680	0.71	KDM4E (0.41)	ALDH1A1CYP1A2CYP3A4CYP2C9HSD17B10
	SCHEMBL1516128	0.71	ALDH1A1 (0.34)	ALDH1A1HSD17B10TSHRHPGDALOX15
	SCHEMBL28730602	0.70	CYP1A2 (0.42)	ALDH1A1L3MBTL1CYP1A2HPGDKCNH2
	SCHEMBL9269074	0.67	MAOB (0.53)	ALDH1A1CYP1A2MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.