Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 4/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11274662 | 1.00 | TRPM8 (0.63) | TRPM8NPC1L3MBTL1BCHEMAOA | |
| SCHEMBL28501196 | 0.81 | NPC1 (0.72) | TRPM8NPC1L3MBTL1BCHEMAOA | |
| SCHEMBL11279078 | 0.79 | NPC1 (0.59) | TRPM8NPC1L3MBTL1BCHEMAOA | |
| SCHEMBL11279073 | 0.79 | NPC1 (0.59) | TRPM8NPC1L3MBTL1BCHEMAOA | |
| SCHEMBL28508248 | 0.79 | NPC1 (0.69) | TRPM8NPC1L3MBTL1BCHEMAOA | |
| SCHEMBL31228779 | 0.78 | NPC1 (0.72) | TRPM8NPC1L3MBTL1BCHEMAOA | |
| SCHEMBL31228704 | 0.78 | NPC1 (0.72) | TRPM8NPC1L3MBTL1BCHEMAOA | |
| SCHEMBL10270783 | 0.78 | TRPM8 (1.00) | TRPM8NPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28408661 | 0.78 | TRPM8 (1.00) | TRPM8NPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL7245709 | 0.77 | L3MBTL1 (0.70) | TRPM8NPC1L3MBTL1BCHEMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335054-A | Process for the preparation of alkenylbenzenecarboxylic acid derivatives and alkenylnaphthalenecarboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1982-06-15 | — | — | US | disclosed |