Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.58 |
| ▸ | PYGL | P06737 | 9/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.49 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.49 |
| ▸ | ITGAL | P20701 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279078 | 1.00 | NPC1 (0.59) | NPC1L3MBTL1TRPM8PYGLBCHE | |
| SCHEMBL13879637 | 0.85 | NPC1 (0.54) | NPC1L3MBTL1TRPM8PYGLBCHE | |
| SCHEMBL28379022 | 0.80 | NPC1 (0.67) | NPC1L3MBTL1TRPM8BCHEMAOA | |
| SCHEMBL11274659 | 0.79 | TRPM8 (0.63) | NPC1L3MBTL1TRPM8BCHEMAOA | |
| SCHEMBL11274662 | 0.79 | TRPM8 (0.63) | NPC1L3MBTL1TRPM8BCHEMAOA | |
| SCHEMBL7623481 | 0.77 | GABRA1 (0.49) | PYGLITGB2ICAM1ITGALPTGS2 | |
| SCHEMBL7623478 | 0.77 | GABRA1 (0.49) | PYGLITGB2ICAM1ITGALPTGS2 | |
| SCHEMBL31228779 | 0.77 | NPC1 (0.72) | NPC1L3MBTL1TRPM8BCHEMAOA | |
| SCHEMBL31228704 | 0.77 | NPC1 (0.72) | NPC1L3MBTL1TRPM8BCHEMAOA | |
| SCHEMBL28501196 | 0.77 | NPC1 (0.72) | NPC1L3MBTL1TRPM8BCHEMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335054-A | Process for the preparation of alkenylbenzenecarboxylic acid derivatives and alkenylnaphthalenecarboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1982-06-15 | — | — | US | disclosed |