Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | CTSL | P07711 | 2/20 | 0.59 |
| ▸ | CTSB | P07858 | 2/20 | 0.59 |
| ▸ | CTSS | P25774 | 2/20 | 0.59 |
| ▸ | CTSK | P43235 | 2/20 | 0.59 |
| ▸ | ACE | P12821 | 3/20 | 0.58 |
| ▸ | TACR1 | P25103 | 2/20 | 0.57 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 2/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28355708 | 0.90 | ALDH1A1 (0.64) | ALDH1A1ALOX15CTSLCTSBCTSS | |
| SCHEMBL11119660 | 0.88 | ACE (0.61) | ALDH1A1ALOX15CTSLCTSBCTSS | |
| SCHEMBL11119655 | 0.88 | ACE (0.61) | ALDH1A1ALOX15CTSLCTSBCTSS | |
| SCHEMBL11119658 | 0.88 | ACE (0.61) | ALDH1A1ALOX15CTSLCTSBCTSS | |
| SCHEMBL13998432 | 0.84 | CTSL (0.64) | ALDH1A1ALOX15CTSLCTSBCTSS | |
| SCHEMBL7151822 | 0.84 | ALDH1A1 (0.74) | ALDH1A1ALOX15CTSLCTSBCTSS | |
| SCHEMBL329686 | 0.84 | ALDH1A1 (0.74) | ALDH1A1ALOX15CTSLCTSBCTSS | |
| SCHEMBL7324257 | 0.83 | ACE (0.70) | CTSLCTSBCTSSCTSKACE | |
| SCHEMBL28356104 | 0.82 | TACR1 (0.64) | ALDH1A1ALOX15CTSLCTSBCTSS | |
| Hydrochloric Acid SCHEMBL7928050 | 0.82 | ALDH1A1 (0.72) | ALDH1A1ALOX15CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329473-A | HYPOTENSIVE AGENTS | SRI INTERNATIONAL | 1982-05-11 | — | — | US | disclosed |