Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11284305 | 0.93 | OPRK1 (0.61) | OPRK1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL4121702 | 0.89 | OPRK1 (0.62) | OPRK1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL11281078 | 0.88 | KMT2A (0.59) | KMT2AMEN1CACNA1BAPBA1SMN1; SMN2 | |
| SCHEMBL11270689 | 0.86 | PGR (0.57) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL23352537 | 0.85 | CACNA1B (0.48) | OPRK1KMT2AMEN1CACNA1BAPBA1 | |
| SCHEMBL11285274 | 0.83 | KMT2A (0.53) | OPRK1KMT2AMEN1CACNA1BAPBA1 | |
| SCHEMBL20660719 | 0.81 | OPRK1 (0.59) | OPRK1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL20660653 | 0.81 | OPRK1 (0.59) | OPRK1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL20660561 | 0.81 | OPRK1 (0.59) | OPRK1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL10620286 | 0.81 | OPRK1 (0.59) | OPRK1KMT2AMEN1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309441-A | HYPOTENSIVE AGENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-01-05 | — | — | US | disclosed |