Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.78 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.78 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11275253 | 0.99 | ADRB2 (0.79) | LMNAHIF1AALDH1A1CYP3A4ADRB2 | |
| Hydrochloric Acid SCHEMBL11289468 | 0.91 | ADRB2 (0.67) | LMNAHIF1AALDH1A1CYP3A4ADRB2 | |
| SCHEMBL11280908 | 0.90 | LMNA (0.65) | LMNAHIF1AALDH1A1CYP3A4ADRB2 | |
| SCHEMBL11292572 | 0.88 | LMNA (0.61) | LMNAHIF1AALDH1A1CYP3A4ADRB2 | |
| SCHEMBL11281801 | 0.88 | LMNA (0.61) | LMNAHIF1AALDH1A1CYP3A4ADRB2 | |
| Dipivefrin SCHEMBL24713 | 0.88 | HIF1A (1.00) | LMNAHIF1AALDH1A1CYP3A4ADRB2 | |
| Dipivefrin SCHEMBL24714 | 0.88 | HIF1A (1.00) | LMNAHIF1AALDH1A1CYP3A4ADRB2 | |
| Dipivefrin SCHEMBL20673238 | 0.88 | HIF1A (1.00) | LMNAHIF1AALDH1A1CYP3A4ADRB2 | |
| Dipivefrin SCHEMBL29710905 | 0.88 | HIF1A (1.00) | LMNAHIF1AALDH1A1CYP3A4ADRB2 | |
| Hydrochloric Acid SCHEMBL11281799 | 0.87 | ADRB2 (0.62) | LMNAHIF1AALDH1A1CYP3A4ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | claimed |
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |