Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11275258 | 0.90 | LMNA (0.78) | LMNAHIF1AALDH1A1CYP3A4ADRB2 | |
| Hydrochloric Acid SCHEMBL11275253 | 0.89 | ADRB2 (0.79) | LMNAHIF1AALDH1A1CYP3A4ADRB2 | |
| SCHEMBL11287921 | 0.88 | LMNA (0.50) | LMNAHIF1AALDH1A1CYP3A4ADRB2 | |
| SCHEMBL11289785 | 0.87 | LMNA (0.48) | LMNAHIF1AALDH1A1CYP3A4ADRB2 | |
| SCHEMBL11277423 | 0.86 | LMNA (0.47) | LMNAHIF1AALDH1A1CYP3A4ADRB2 | |
| SCHEMBL11280916 | 0.86 | HIF1A (0.58) | LMNAHIF1AALDH1A1CYP3A4ADRB2 | |
| SCHEMBL11283474 | 0.85 | LMNA (0.46) | LMNAHIF1AALDH1A1CYP3A4ADRB2 | |
| SCHEMBL11279956 | 0.82 | HIF1A (0.54) | LMNAHIF1AALDH1A1CYP3A4ADRB2 | |
| Hydrochloric Acid SCHEMBL11289468 | 0.82 | ADRB2 (0.67) | LMNAHIF1AALDH1A1CYP3A4ADRB2 | |
| SCHEMBL11282273 | 0.80 | PMP22 (0.46) | LMNAHIF1AADRB2PMP22KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | claimed |
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |