Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 2/20 | 0.32 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 10/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 7/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272118 | 0.91 | TOP2A (0.32) | ALDH1A1TOP2ATOP2BBRAFMAPK14 | |
| SCHEMBL11273016 | 0.84 | ALDH1A1 (0.36) | ALDH1A1TDP1TOP2ATOP2BEGLN2 | |
| SCHEMBL11277961 | 0.81 | ALDH1A1 (0.38) | ALDH1A1TDP1 | |
| SCHEMBL11274778 | 0.80 | TOP2A (0.32) | ALDH1A1TDP1TOP2ATOP2BBRAF | |
| SCHEMBL11276790 | 0.80 | ALDH1A1 (0.38) | ALDH1A1TDP1EGLN2EGLN1KDM4E | |
| SCHEMBL11274889 | 0.79 | L3MBTL1 (0.34) | ALDH1A1TDP1TOP2ATOP2BEGLN2 | |
| SCHEMBL11283712 | 0.79 | TOP2A (0.37) | TOP2ATOP2BBRAFMAPK14ALOX15 | |
| SCHEMBL11300912 | 0.78 | TDP1 (0.58) | ALDH1A1TDP1MEN1KMT2ALMNA | |
| SCHEMBL11272139 | 0.77 | ALDH1A1 (0.36) | ALDH1A1TDP1TOP2ATOP2BKDM4E | |
| SCHEMBL11281949 | 0.76 | PTGS1 (0.31) | ALDH1A1TDP1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338326-A | PESTICIDES | UNION CARBIDE CORPORATION (US) | 1982-07-06 | — | — | US | disclosed |