Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272118 | 0.89 | TOP2A (0.32) | TOP2ATOP2BMAPTKDM4EKMT2A | |
| SCHEMBL11267772 | 0.82 | P2RX3 (0.32) | KMT2AMEN1L3MBTL1 | |
| SCHEMBL11281016 | 0.82 | LMNA (0.33) | LMNAHPGDTSHRL3MBTL1 | |
| SCHEMBL11275322 | 0.80 | ALDH1A1 (0.36) | TOP2ATOP2BMAPTKDM4EKMT2A | |
| SCHEMBL11265443 | 0.78 | L3MBTL1 (0.31) | ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11273157 | 0.76 | PLA2G10 (0.39) | TOP2ATOP2BMAPTKDM4ETP53 | |
| SCHEMBL11281949 | 0.75 | PTGS1 (0.31) | ALDH1A1LMNAHTTTDP1 | |
| SCHEMBL11274589 | 0.74 | P2RX3 (0.33) | KMT2AMEN1L3MBTL1 | |
| SCHEMBL11274546 | 0.74 | MEN1 (0.33) | KMT2AMEN1 | |
| SCHEMBL11272139 | 0.74 | ALDH1A1 (0.36) | TOP2ATOP2BKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338326-A | PESTICIDES | UNION CARBIDE CORPORATION (US) | 1982-07-06 | — | — | US | disclosed |