Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 3/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | DRD1 | P21728 | 2/20 | 0.56 |
| ▸ | DRD4 | P21917 | 2/20 | 0.56 |
| ▸ | DRD5 | P21918 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11272389 | 0.98 | DRD3 (0.54) | DRD3DRD2DRD1DRD4DRD5 | |
| Acetic Acid SCHEMBL11278289 | 0.91 | HRH3 (0.48) | DRD3DRD2DRD1DRD4DRD5 | |
| SCHEMBL23309922 | 0.84 | HIF1A (0.77) | DRD3DRD2DRD1DRD4DRD5 | |
| SCHEMBL31366413 | 0.84 | HIF1A (0.77) | DRD3DRD2DRD1DRD4DRD5 | |
| Hydrochloric Acid SCHEMBL11278346 | 0.83 | SIGMAR1 (0.45) | DRD3DRD2DRD1DRD4DRD5 | |
| Hydrochloric Acid SCHEMBL11279264 | 0.81 | HRH3 (0.51) | DRD3DRD2DRD1DRD4DRD5 | |
| Hydrochloric Acid SCHEMBL11280275 | 0.81 | HRH3 (0.47) | HRH3KDM4EBCHE | |
| Hydrochloric Acid SCHEMBL11280503 | 0.79 | HTR1A (0.52) | DRD3CYP3A4CYP2D6HRH3PMP22 | |
| SCHEMBL9670817 | 0.78 | SIGMAR1 (0.58) | DRD3DRD1ADRA1AHRH3SIGMAR1 | |
| SCHEMBL8847943 | 0.77 | NPC1 (0.55) | CYP3A4HIF1AHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327022-A | Heterocyclic alkyl naphthols | STERLING DRUG INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4169108-A | 5(OR 6)-[(Substituted-amino)alkyl]-2,3-naphthalenediols | STERLING DRUG INC. (US) | 1979-09-25 | — | — | US | disclosed |