Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.77 |
| ▸ | DRD2 | P14416 | 3/20 | 0.77 |
| ▸ | DRD1 | P21728 | 3/20 | 0.77 |
| ▸ | DRD4 | P21917 | 3/20 | 0.77 |
| ▸ | DRD5 | P21918 | 3/20 | 0.77 |
| ▸ | DRD3 | P35462 | 3/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.77 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.77 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.77 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.77 |
| ▸ | TSHR | P16473 | 2/20 | 0.77 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.74 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | IGF1R | P08069 | 1/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23309922 | 1.00 | HIF1A (0.77) | HIF1AHSD17B10DRD2DRD1DRD4 | |
| SCHEMBL467093 | 0.87 | DRD2 (1.00) | HIF1AHSD17B10DRD2DRD1DRD4 | |
| SCHEMBL29368857 | 0.87 | DRD2 (1.00) | HIF1AHSD17B10DRD2DRD1DRD4 | |
| Hydrochloric Acid SCHEMBL4305739 | 0.85 | DRD2 (0.96) | HIF1AHSD17B10DRD2DRD1DRD4 | |
| Bromide SCHEMBL1321255 | 0.85 | KDM4E (1.00) | HIF1AHSD17B10DRD2DRD1DRD4 | |
| SCHEMBL11275413 | 0.84 | DRD3 (0.56) | HIF1AHSD17B10DRD2DRD1DRD4 | |
| Hydrochloric Acid SCHEMBL11272389 | 0.82 | DRD3 (0.54) | HIF1AHSD17B10DRD2DRD1DRD4 | |
| Dopamine SCHEMBL28956662 | 0.81 | KDM4E (0.75) | HIF1AHSD17B10DRD2DRD1DRD4 | |
| SCHEMBL6674754 | 0.81 | DRD2 (0.87) | HIF1AHSD17B10DRD2DRD1DRD4 | |
| SCHEMBL18183637 | 0.81 | DRD2 (0.66) | HIF1AHSD17B10DRD2DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12208108-B2 | Drug targets of delayed aging and human brain diseases | TEXAS TECH UNIVERSITY SYSTEM (US) | 2025-01-28 | — | — | US | disclosed |
| US-12208108-B2 | Drug targets of delayed aging and human brain diseases | TEXAS TECH UNIVERSITY SYSTEM (US) | 2025-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12208108-B2 | Drug targets of delayed aging and human brain diseases | DNM1L, DNM1, DNM2 | HIF1A 1699/4885HSD17B10 3017/4885DRD2 855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.