Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GGT1 | P19440 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1043130 | 0.86 | PTGS2 (0.59) | MAPK1KDM4EHSD17B10PTGS2ALDH1A1 | |
| SCHEMBL9371172 | 0.79 | MAPK1 (0.77) | MAPK1KDM4EHSD17B10PTGS2ALDH1A1 | |
| Dipyrocetyl SCHEMBL26164 | 0.77 | MAPK1 (1.00) | MAPK1KDM4EHSD17B10PTGS2ALDH1A1 | |
| Dipyrocetyl SCHEMBL29508594 | 0.77 | MAPK1 (1.00) | MAPK1KDM4EHSD17B10PTGS2ALDH1A1 | |
| SCHEMBL5212814 | 0.76 | MAPK1 (0.71) | MAPK1KDM4EHSD17B10PTGS2ALDH1A1 | |
| Dipyrocetyl SCHEMBL11121474 | 0.76 | MAPK1 (0.96) | MAPK1KDM4EHSD17B10PTGS2ALDH1A1 | |
| SCHEMBL3939105 | 0.76 | MAPK1 (0.72) | MAPK1KDM4EHSD17B10PTGS2ALDH1A1 | |
| SCHEMBL415898 | 0.76 | MAPK1 (0.72) | MAPK1KDM4EHSD17B10PTGS2ALDH1A1 | |
| SCHEMBL7665814 | 0.76 | MAPK1 (0.72) | MAPK1KDM4EHSD17B10PTGS2ALDH1A1 | |
| SCHEMBL31434426 | 0.76 | MAPK1 (0.72) | MAPK1KDM4EHSD17B10PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341776-A | BACTERICIDES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1982-07-27 | — | — | US | disclosed |
| US-4328224-A | ANTIBIOTICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1982-05-04 | — | — | US | disclosed |
| US-4301161-A | BACTERICIDES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1981-11-17 | — | — | US | disclosed |
| US-4298605-A | ANTIBIOTICS, BACTERICIDES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1981-11-03 | — | — | US | disclosed |
| US-4229348-A | Penicillanic acid derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1980-10-21 | — | — | US | disclosed |