Sugi Predict

Sugi Predict / Compounds / SCHEMBL415898

SCHEMBL415898

SCHEMBL415898

CC(=O)Oc1cccc(C(=O)Cl)c1OC(C)=O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 1/20 0.72
▸ KDM4E B2RXH2 6/20 0.53
▸ HSD17B10 Q99714 5/20 0.53
▸ HPGD P15428 4/20 0.53
▸ ALDH1A1 P00352 3/20 0.53
▸ BLM P54132 2/20 0.53
▸ TDP1 Q9NUW8 2/20 0.53
▸ PTGS2 P35354 2/20 0.53
▸ ESR1 P03372 1/20 0.53
▸ ITGB3 P05106 1/20 0.53
▸ ITGA2B P08514 1/20 0.53
▸ HMGB1 P09429 1/20 0.53
▸ TSHR P16473 1/20 0.53
▸ GGT1 P19440 1/20 0.53
▸ PTGS1 P23219 1/20 0.53
▸ NAPRT Q6XQN6 1/20 0.53
▸ FNTA P49354 1/20 0.51
▸ FNTB P49356 1/20 0.51
▸ LMNA P02545 1/20 0.47
▸ CYP1A2 P05177 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8658218 0.90 MAPK1 (0.58) MAPK1KDM4EHSD17B10HPGDALDH1A1
SCHEMBL9371172 0.85 MAPK1 (0.77) MAPK1KDM4EHSD17B10HPGDALDH1A1
Dipyrocetyl SCHEMBL29508594 0.84 MAPK1 (1.00) MAPK1KDM4EHSD17B10HPGDALDH1A1
Dipyrocetyl SCHEMBL26164 0.84 MAPK1 (1.00) MAPK1KDM4EHSD17B10HPGDALDH1A1
SCHEMBL1773882 0.84 MAPK1 (0.50) MAPK1KDM4EHSD17B10HPGDALDH1A1
SCHEMBL30269568 0.83 PTGS2 (0.69) MAPK1KDM4EHSD17B10HPGDALDH1A1
SCHEMBL1332285 0.83 PTGS2 (0.69) MAPK1KDM4EHSD17B10HPGDALDH1A1
SCHEMBL133699 0.83 PTGS2 (0.69) MAPK1KDM4EHSD17B10HPGDALDH1A1
SCHEMBL5212814 0.82 MAPK1 (0.71) MAPK1KDM4EHSD17B10HPGDALDH1A1
SCHEMBL7665814 0.82 MAPK1 (0.72) MAPK1KDM4EHSD17B10HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2404891-B1 PREPARATION METHOD OF ACYLBENZENES DSM IP ASSETS BV (NL) 2015-09-02 — — EP claimed
US-8642800-B2 Preparation method of acylbenzenes DSM IP ASSETS B.V. (NL) 2014-02-04 — — US claimed
US-20120022284-A1 PREPARATION METHOD OF ACYLBENZENES DSM IP ASSETS B.V. (NL) 2012-01-26 — — US claimed
EP-2404891-A1 PREPARATION METHOD OF ACYLBENZENES DSM IP Assets B.V. (NL) 2012-01-11 — — EP claimed
US-20260009790-A1 FLUID ANALYSES AND SENSOR CONSTRUCTS EMPLOYING HEXASUBSTITUTED BENZENES COUNTERTRACE LLC (US) 2026-01-08 — — US disclosed
US-12422430-B2 Fluid analyses and sensor constructs employing hexasubstituted benzenes Countertrace, LLC (US) 2025-09-23 — — US disclosed
US-12338196-B2 Hexasubstituted benzenes, surfaces modified therewith, and associated methods Countertrace, LLC (US) 2025-06-24 — — US disclosed
US-20220283152-A1 FLUID ANALYSES AND SENSOR CONSTRUCTS EMPLOYING HEXASUBSTITUTED BENZENES Countertrace, LLC (US) 2022-09-08 — — US disclosed
EP-4028378-A1 HEXASUBSTITUTED BENZENES, SURFACES MODIFIED THEREWITH, AND ASSOCIATED METHODS Countertrace LLC (US) 2022-07-20 — — EP disclosed
EP-4028767-A1 FLUID ANALYSES AND SENSOR CONSTRUCTS EMPLOYING HEXASUBSTITUTED BENZENES Countertrace LLC (US) 2022-07-20 — — EP disclosed
US-20220144733-A1 HEXASUBSTITUTED BENZENES, SURFACES MODIFIED THEREWITH, AND ASSOCIATED METHODS Countertrace, LLC (US) 2022-05-12 — — US disclosed
US-20220144733-A1 HEXASUBSTITUTED BENZENES, SURFACES MODIFIED THEREWITH, AND ASSOCIATED METHODS Countertrace, LLC (US) 2022-05-12 — — US disclosed
EP-0267733-A2 Cephalosporin compounds, process for their preparation and pharmaceutical compositions containing them ZENECA Pharma S.A. (FR) 1988-05-18 — — EP disclosed
EP-0265185-A2 Cephalosporins, processes for their preparation and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1988-04-27 — — EP disclosed
EP-0251143-A1 2-Oxo-1-[[(Substituted Sulfonyl)Amino]-Carbonyl]Azetidines Bristol-Myers Squibb GmbH (DE) 1988-01-07 — — EP disclosed
EP-0115820-A2 Cephalosporin derivatives and process for their preparation Kaken Pharmaceutical Co., Ltd. (JP) 1984-08-15 — — EP disclosed
US-4341776-A BACTERICIDES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1982-07-27 — — US disclosed
US-4328224-A ANTIBIOTICS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1982-05-04 — — US disclosed
US-4301161-A BACTERICIDES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1981-11-17 — — US disclosed
US-4298605-A ANTIBIOTICS, BACTERICIDES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1981-11-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12338196-B2 Hexasubstituted benzenes, surfaces modified therewith, and associated methods CBR3, BRD3, CBX3 MAPK1 3731/4885KDM4E 734/4885HSD17B10 2465/4885
US-20260009790-A1 FLUID ANALYSES AND SENSOR CONSTRUCTS EMPLOYING HEXASUBSTITUTED BENZENES CSTB, FGB, S100B MAPK1 1719/4885KDM4E 4427/4885HSD17B10 2579/4885
US-20120022284-A1 PREPARATION METHOD OF ACYLBENZENES ACACB, SDHB, TET2 MAPK1 4209/4885KDM4E 233/4885HSD17B10 215/4885
US-20220144733-A1 HEXASUBSTITUTED BENZENES, SURFACES MODIFIED THEREWITH, AND ASSOCIATED METHODS CBR3, BRD3, CBX3 MAPK1 3731/4885KDM4E 734/4885HSD17B10 2465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.