Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 3/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11328971 | 0.82 | MEN1 (0.44) | MEN1KMT2AIKBKBALDH1A1NPC1 | |
| SCHEMBL11264202 | 0.73 | MEN1 (0.64) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL11275588 | 0.68 | MAPT (0.46) | MEN1KMT2AIKBKBALDH1A1NPC1 | |
| SCHEMBL9298461 | 0.67 | NPSR1 (0.46) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL27833925 | 0.66 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL11262954 | 0.65 | CYP11B2 (0.49) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL21938127 | 0.65 | GABRA1 (0.54) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL2325695 | 0.64 | ADORA2A (0.67) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL21938128 | 0.64 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL31009002 | 0.64 | ADORA2A (0.67) | MEN1KMT2AALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310551-A | Pharmacologically active substituted 1,2,4-triazines | DIAMOND SHAMROCK CORPORATION (US) | 1982-01-12 | — | — | US | disclosed |
| US-4251527-A | ANTIINFLAMMATORY AGENTS | DIAMOND SHAMROCK CORPORATION (US) | 1981-02-17 | — | — | US | disclosed |
| US-4157392-A | HYPOTENSIVE AGENTS, ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS AND NERVOUS SYSTEM EFFECTS | DIAMOND SHAMROCK CORPORATION (US) | 1979-06-05 | — | — | US | disclosed |