Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11274609 | 0.88 | GAA (0.51) | ALDH1A1NPC1HTTP2RY1RAB9A | |
| SCHEMBL11498392 | 0.84 | KMT2A (0.57) | ALDH1A1NPC1HTTP2RY1RAB9A | |
| SCHEMBL11275782 | 0.83 | NPC1 (0.47) | ALDH1A1NPC1HTTTHRBP2RY1 | |
| SCHEMBL11636558 | 0.82 | ALDH1A1 (0.66) | ALDH1A1NPC1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL11265505 | 0.80 | KDM4E (0.55) | ALDH1A1NPC1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL9852812 | 0.79 | NPSR1 (0.47) | ALDH1A1NPC1KDM4EHTTTHRB | |
| Chlorsulfuron SCHEMBL54874 | 0.79 | ALDH1A1 (0.61) | ALDH1A1NPC1KDM4ESMN1; SMN2KMT2A | |
| Chlorsulfuron SCHEMBL11325389 | 0.79 | ALDH1A1 (0.61) | ALDH1A1NPC1KDM4ESMN1; SMN2KMT2A | |
| Chlorsulfuron SCHEMBL7902297 | 0.79 | ALDH1A1 (0.61) | ALDH1A1NPC1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL11155233 | 0.79 | ALDH1A1 (0.61) | ALDH1A1NPC1KDM4ESMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001485-B1 | HERBICIDAL SULPHONAMIDES, THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND USE THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-05-12 | — | — | EP | claimed |
| US-4221585-A | N-[(2,6-Dimethoxypyrimidin-4-yl)]aminocarbonyl benzene sulfonamides and their herbicidal compositions and methods of use | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-09-09 | — | — | US | claimed |
| EP-0001485-A2 | Herbicidal sulphonamides, their preparation, compositions containing them and use thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-04-18 | — | — | EP | claimed |
| EP-0001485-B1 | HERBICIDAL SULPHONAMIDES, THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND USE THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-05-12 | — | — | EP | disclosed |
| US-4221585-A | N-[(2,6-Dimethoxypyrimidin-4-yl)]aminocarbonyl benzene sulfonamides and their herbicidal compositions and methods of use | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-09-09 | — | — | US | disclosed |
| EP-0001485-A2 | Herbicidal sulphonamides, their preparation, compositions containing them and use thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-04-18 | — | — | EP | disclosed |